Recombinant Rat Lamina-associated polypeptide 2, isoform beta (Tmpo)

Code CSB-CF730803RA
MSDS
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names
Tmpo
Uniprot No.
Alternative Names
Tmpo; Lap2; Lamina-associated polypeptide 2, isoform beta; Thymopoietin isoform beta; TP beta
Species
Rattus norvegicus (Rat)
Expression Region
2-452
Target Protein Sequence
PEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLAAGANSKG PPDFSSDEEREPTPVLGSGASVGRGRGAVGRKATKKTDKPRPEDKDDLDVTELSNEELLE QLVRYGVNPGPIVGTTRKLYEKKLLKLREQGAESRSSTPLPTVSSSAENTRQNGSNDSDR YSDNDEDSKIELKLEKREPLKGRAKTPVTLKQRRIEHNQSYSEAGVTETEWTSGSSKGGP LQALTRESTRGSRRTPRRRVEPSQHFRVDGAVISESTPIAETIKASSNDSLVANRLTGNF KHASSILPITEFSDITRRTPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISAS CRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSVPMWIKMLLFAL VAGFLFLVYQAMETNQGNPFTNFLQDTKISN
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Binds directly to lamin B1 and chromosomes in a mitotic phosphorylation-regulated manner. May play an important role in nuclear envelope reassembly at the end of mitosis and/or anchoring of the nuclear lamina and interphase chromosomes to the nuclear envelope.
Gene References into Functions
  1. LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly PMID: 15546916
  2. In agreement with its regulation by E2F, LAP2alpha over expression in primary tumors was found to be correlated with tumor proliferation rate PMID: 16760672
Subcellular Location
Nucleus inner membrane; Single-pass type II membrane protein. Chromosome. Note=Tightly associated with the nuclear lamina.
Protein Families
LEM family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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