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| Code | CSB-E07309h |
| Size | 96T,5×96T,10×96T |
| Price | Request a Quote or Start an on-line Chat |
| Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now |
This human MPIF-1 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of human MPIF-1 in multiple samples, including serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the MPIF-1 levels in the sample and is measured at 450 nm through a microplate reader.
MPIF-1, also CCL23, MIP-3, or CKβ8, is produced by eosinophils, monocyte-derived dendritic cells, and IL-1β-activated monocytes. It serves as a chemoattractant for dendritic cells, resting T lymphocytes, and monocytes. CCL23 is associated with the pathophysiology of various inflammatory conditions such as rheumatoid arthritis, chronic rhinosinusitis, chronic kidney dysfunction, and systemic sclerosis. Circulating CCL23 levels have also been related to markers of atheroprogression, such as aortic wall thickness and plaque burden. In terms of cancer, CCL23 appears to have pro- and anti-cancer properties. A study showed that CCL23 was necessary and sufficient to promote the migration of ovarian cancer. Another study demonstrated that CCL23 is downregulated in hepatocellular carcinoma (HCC) tissues and cell lines.
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