CHGA Monoclonal Antibody

Datasheet
Code CSB-MA0053441A0m
Product Type Monoclonal Antibody
Size US$350Purchase it in Cusabio online store
(Shop online in the US. Customers outside the US,
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Uniprot No. P10645
Image
  • Immunohistochemical of paraffin-embedded Human small intestine tissue using CSB-MA0053441A0m(1D7-3D5) at dilution of 1:200.

  • Immunohistochemical of paraffin-embedded Human pancreas tissue using CSB-MA0053441A0m(1D7-3D5) at dilution of 1:200.

  • All lanes: Chromogranin-A transfected E.coli lysate
    lane 1:Mouse Anti--6*his monoclonal antibody at 1μg/ml
    lane 2 : Mouse anti- Chromogranin-A monoclonal antibody at 1μg/ml
    Predicted band size : 52Kd
    Observed band size : 52kd

Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant CHGA Protein
Raised in mouse
Species Reactivity Human
Specificity specific for Recombinant CHGA Protein denatured and native forms
Tested Applications ELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500
Relevance Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) , and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors. However, CgA is not a tumor-specific antigen for NETs, and an abnormal concentration has been described in some non-malignant diseases such as renal failure, heart failure, proton pump inhibition, gastritis, hypertension, or patients with liver diseases.
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%,protein G purifed
Isotype IgG1
Clonality monoclonal
Alias Chromogranin-A,CgA,Pituitary secretory protein I,SP-I,Vasostatin II,CHGA
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. 1A11C11
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