Recombinant Human Serum amyloid A-1 protein(SAA1) (Active)


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Code CSB-AP000441HU
Product Type Other
Size US$112Purchase it in Cusabio online store
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Uniprot No. P0DJI8
Lead Time 5-10 business days
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Storage Buffer 0.2 μm filtered concentrated solution in 20 mM Tris-HCl, pH 9.0, 150 mM NaCl,Lyophilized
Alias SAA,; Serum amyloid protein A2-104,; Serum amyloid protein A3-104,; Serum amyloid protein A2-103,; Serum amyloid protein A2-102
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence RSFFSFLGEA FDGARDMWRA YSDMREANYI GSDKYFHARG NYDAAKRGPG GVWAAEAISD ARENIQRFFG HGAEDSLADQ AANEWGRSGK DPNHFRPAGL PEKY
Research Area Immunology
Source E.Coli
Gene Names SAA1
Expression Region 19-122aa
Tag Info Tag-Free
Mol. Weight 11.7 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3839415; 3183061; 1656519; 16554811; 15489334; 1971508; 7115671; 1546977; 6155694; 5055786; 5056669; 4816450; 1463770; 1259755; 11946204; 3442653; 12973732; 8783012; 8670280; 10211414; 12606051; 8512321; 24275569; 24706838
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Function Major acute phase protein.
Involvement in disease Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
Subcellular Location Secreted
Protein Families SAA family
Tissue Specificity Expressed by the liver; secreted in plasma (at protein level).
Database Links

HGNC: 10513

OMIM: 104750

KEGG: hsa:6288

STRING: 9606.ENSP00000348918

UniGene: Hs.632144

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