Recombinant Human Syndecan-4 protein(SDC4) (Active)

In Stock
Code CSB-AP000331HU
Product Type Other
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P31431
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias SYND4, Ryudocan core protein
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The specific activity is determined by binding ability in a functional ELISA. Immobilized rHuSYND4 at 500 ng/ml (100 μl/well) can bind rHubFGF with a linear range of 0.1-10 ng/ml.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence ESIRETEVID PQDLLEGRYF SGALPDDEDV VGPGQESDDF ELSGSGDLDD LEDSMIGPEV VHPLVPLDNH IPERAGSGSQ VPTEPKKLEE NEVIPKRISP VEESEDVSNK VSMSSTVQGS NIFERTE
Research Area Signal Transduction
Source E.coli
Gene Names SDC4
Expression Region 19-145aa
Tag Info Tag-Free
Mol. Weight 13.9 kDa
Protein Description Partial
PubMed ID 1500433; 7916598; 8797100; 14702039; 11780052; 15489334; 8889549; 9169435; 14675776; 16007225; 21269460; 24275569; 11456484; 12842047; 16533050
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Function Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP
Subcellular Location Isoform 1: Membrane, Single-pass type I membrane protein, Secreted
Protein Families Syndecan proteoglycan family
Tissue Specificity Expressed in epithelial and fibroblastic cells.
Database Links

HGNC: 10661

OMIM: 600017

KEGG: hsa:6385

STRING: 9606.ENSP00000361818

UniGene: Hs.632267

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