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| Code | CSB-PA040368 |
| Size | US$299 How to order? |
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| Have Questions? | Leave a Message or Start an on-line Chat |
| Uniprot No. | Q9H172 | ||||||
| Target Names | ABCG4 | ||||||
| Alternative Names | ABCG4; WHITE2; ATP-binding cassette sub-family G member 4 | ||||||
| Raised in | Rabbit | ||||||
| Species Reactivity | Human,Mouse | ||||||
| Immunogen | Fusion protein of Human ABCG4 | ||||||
| Immunogen Species | Homo sapiens (Human) | ||||||
| Conjugate | Non-conjugated | ||||||
| Isotype | IgG | ||||||
| Purification Method | Antigen affinity purification | ||||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
| Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | ||||||
| Form | Liquid | ||||||
| Tested Applications | ELISA,WB | ||||||
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| Protocols | ELISA Protocol Western Blotting(WB) Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
ATP-dependent transporter of the ATP-binding cassette (ABC) family that may be involved in the cellular efflux of sterols, in particular cholesterol and desmosterol (a cholesterol precursor), to high-density lipoprotein (HDL). May play an important role in the removal of amyloid-beta peptides from brain, in a process that can be antagonized by desmosterol. However it is unclear whether ABCG4 can directly transport amyloid-beta peptides or whether peptide export may be facilitated due to changes in the membrane lipid environment. Induces apoptosis in various cells.
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| Gene References into Functions |
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| Subcellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. |
| Protein Families | ABC transporter superfamily, ABCG family, Eye pigment precursor importer (TC 3.A.1.204) subfamily |
| Tissue Specificity | Expressed specifically in the brain and the eye. |
| Database Links |
HGNC: 13884 OMIM: 607784 KEGG: hsa:64137 STRING: 9606.ENSP00000304111 UniGene: Hs.126378 |
