Recombinant Chicken Visual system homeobox 2 (VSX2)

Code CSB-YP025939CH
MSDS
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Source Yeast
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Code CSB-EP025939CH
MSDS
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Source E.coli
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Code CSB-EP025939CH-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP025939CH
MSDS
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Source Baculovirus
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Code CSB-MP025939CH
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
VSX2
Uniprot No.
Alternative Names
VSX2; CHX10Visual system homeobox 2; Ceh-10 homeodomain-containing homolog; Homeobox protein CHX10
Species
Gallus gallus (Chicken)
Expression Region
1-377
Target Protein Sequence
MTGKAGAALA PSLPGKPKPD GAAAAAPPPP PPAAGAKPSS GPTPPRCTGF GIQEILGLNK EPPSHPRAAL DSLPAGHLLA ARSVLSPAGV GGVGMGLLGA GGIPGFYAQP TFLEVLSDPQ SVHLQPLARA PGQLDSSQTA SSDSEDVSSS DRKMSKSSLN QSKKRKKRRH RTIFTSYQLE ELEKAFNEAH YPDVYAREML AMKTELPEDR IQVWFQNRRA KWRKREKCWG RSSVMAEYGL YGAMVRHSIP LPESILKSAK DGIMESCAPW LLGMHKKSLE AAAEAGRKTE VERQALPKLD KGDKEERGSD PKTAISQEEL RENSIAALRA KAQEHSTKVL GTIAGDTPRK PEKGEEVAED ERQTEKSSAS QKEEKLI
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Acts as a transcriptional regulator. Plays a significant role in the specification and morphogenesis of the sensory retina. Mediates differentiation of V2a interneurons by repression of motor neuron gene transcription, via competitively binding to response elements that are activated by the ISL1-LHX3 complex. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells.
Gene References into Functions
  1. Chx10 can function as a cell autonomous regulator of the regional identity in the primordial retina, presumably through a downstream transcriptional cascade PMID: 27001188
  2. CHX10 and VSX1 may control retinal bipolar cell specification or differentiation by repressing genes required for the development of other cell types PMID: 15647262
  3. Chx10 expression in subsets of retinal progenitor cells and bipolar ells requires a POU factor binding site upstream of the Chx10 gene PMID: 15893976
  4. CHX10 may target specific motifs to inhibit rod photoreceptor gene expression in bipolar cells PMID: 16236706
Subcellular Location
Nucleus.
Protein Families
Paired homeobox family
Tissue Specificity
Retina and spinal cord.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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