Recombinant Human Cysteine-rich PAK1 inhibitor (CRIPAK)

Code CSB-YP005972HU
MSDS
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Source Yeast
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Code CSB-EP005972HU
MSDS
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Source E.coli
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Code CSB-EP005972HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP005972HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP005972HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
CRIPAK
Uniprot No.
Alternative Names
CRIPAKCysteine-rich PAK1 inhibitor; CRIPak
Species
Homo sapiens (Human)
Expression Region
1-446
Target Protein Sequence
MHEPSLCANV ECPPAHTCPC GVPACSCAHV ECPPAHTCRC GVPACSHMPM WSARLLTRAH VECPPAHTRV HVECPPAHVP MWSAHLLTCA DVECHLLTHV PMWSARLLTC PCGVPACSHV PMRSARLLTR AHAECPPAHT CPCGVPACSH VPMRSARLLT RADVECPPAH TCPCGVPACS HVPTWSARLI TRAHVECSPA HTCRCGVPAC SHVPMWSVRL LTRADAECPP AHTCRCGVPA CSHVPMWSAR LLTCRCGVPA CSHVPMWSAR LLTCRCGVPA CSHVPMWSAR LLTRAHVECP PAHTCRRGVP ACSRAHMECP PAHTCHCGVP ACSHTCRCGV PACSHVPMWS ARLLTRAHVE CPPAHTRAHV ECPPAHTCPC GVPACSHTCP CGVPACSHKA LAWWFCRFPV LPAESDAVTV HSTHGGFLIR FYVKDPFYIS LHLEIT
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Putative negative regulator of PAK1. It has been suggested that the lost of CRIPAK in breast tumors might contribute to hormonal independence.
Subcellular Location
Cytoplasm. Membrane. Nucleus. Note=Translocated to the nuclear compartment upon hormonal treatment by estrogen.
Tissue Specificity
Widely expressed with a highest expression observed in trachea, prostate and adrenal glands. Expressed in many cancer cell lines including breast cancer cells.
Database Links

HGNC: 26619

OMIM: 610203

KEGG: hsa:285464

STRING: 9606.ENSP00000323978

UniGene: Hs.26410

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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