Recombinant Human Cysteine-rich secretory protein 1 (CRISP1)

Code CSB-YP005974HU
MSDS
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Source Yeast
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Code CSB-EP005974HU
MSDS
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Source E.coli
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Code CSB-EP005974HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP005974HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP005974HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
CRISP1
Uniprot No.
Alternative Names
Acidic epididymal glycoprotein homolog; Acidic epididymal glycoprotein like 1; AEG like protein; AEG related protein; AEG-like protein; AEGL1; ARP; CRIS1_HUMAN; CRISP-1; CRISP1; Cysteine rich secretory protein 1; Cysteine rich secretory protein 1 delta; Cysteine-rich secretory protein 1; HSCRISP1D; HSCRISP1G; HUMARP; Protein DE like
Species
Homo sapiens (Human)
Expression Region
22-249
Target Protein Sequence
KKKSARDQF NKLVTDLPNV QEEIVNIHNA LRRRVVPPAS NMLKMSWSEE AAQNARIFSK YCDMTESNPL ERRLPNTFCG ENMHMTSYPV SWSSVIGVWY SESTSFKHGE WTTTDDDITT DHYTQIVWAT SYLIGCAIAS CRQQGSPRYL YVCHYCHEGN DPETKNEPYK TGVPCEACPS NCEDKLCTNP CIYYDEYFDC DIQVHYLGCN HSTTILFCKA TCLCDTEIK
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May have a role in sperm-egg fusion and maturation.
Gene References into Functions
  1. Epididymal CRISP1 mediates sperm-zona pellucida binding through its interaction with ZP3. PMID: 24334245
  2. Seminal CRISP1 combined with neutral alpha glucosidase activity can potentially distinguish between obstructive and nonobstructive azoospermia. PMID: 23987519
  3. CRISP1 was in the seminal plasma of normal and vasovasostomized men, but not in that of vasectomized men. The soluble concentration of CRISP1 was significantly higher in the seminal plasma of vasovasostomized men as compared with that from normal men. PMID: 20378925
Subcellular Location
Note=Located in the lumen and epithelium of distal ductus efferentes and epididymal ducts, and on the postacrosomal region of the sperm head.
Protein Families
CRISP family
Tissue Specificity
Caput, corpus, and cauda regions of the epididymis, the ductus deferens, sperm and seminal plasma.
Database Links

HGNC: 304

OMIM: 601193

KEGG: hsa:167

STRING: 9606.ENSP00000338276

UniGene: Hs.109620

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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