Code | CSB-EP618010HU |
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Size | $224 |
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E.coli-expressed Recombinant Human Transcriptional enhancer factor TEF-3 (TEAD4) is a partial-length protein containing 361 amino acids. It carries a 6xHis-tag at the N-terminus. Its expression region is the 74-434aa of the human TEAD4 protein. The SDS-PAGE analysis determined its purity greater than 90% and showed a molecular weight band of about 45 kDa. This protein is in-stock so that it will reach your lab bench faster. In addition to serving as an immunogen for antibody synthesis, the recombinant TEAD4 protein may also be used in the studies of epigenetics and nuclear signaling.
TEAD4 is a transcriptional enhancer factor widely expressed in eukaryotic cells. Studies have uncovered that TEAD4 is involved in the multi-level dysregulation and oncogenic characteristics of gastric cancer (GC) and the development of pancreatic cancer. Its transcriptional coactivator Yes-associated protein (YAP) is a major regulator of organ size and proliferation, and increased YAP/TEAD4 activity is correlated to cancer progression and metastasis. Biswarup Saha etc. revealed that the Hippo signaling effector TEAD4 is indispensable for the establishment of pregnancy in a postimplantation mammalian embryo.
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In terms of the yap binding domain of tead4, is it palmitoylated?
CSB-EP618010HU 74-434aa, which belongs to the yap binding domain, may be palmitoylated, but we have not done relevant verification.