Transcriptional enhancer factor TEF-3 is a protein in humans that is encoded by TEAD4 gene. Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
The following TEAD4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TEAD4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA023366GA01HU | TEAD4 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA618010LA01HU | TEAD4 Antibody |
Human | ELISA, WB, IHC |
CSB-PA618010LC01HU | TEAD4 Antibody, FITC conjugated |
Human | |
CSB-PA618010LD01HU | TEAD4 Antibody, Biotin conjugated |
Human | ELISA |
TEAD4 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA737076ZA01MO | Tead4 Antibody |
Mus musculus | ELISA, WB (ensure identification of antigen) |
TEAD4 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP023366CH CSB-EP023366CH CSB-BP023366CH CSB-MP023366CH CSB-EP023366CH-B |
Recombinant Chicken Transcriptional enhancer factor TEF-3 (TEAD4) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TEAD4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP618010HU CSB-MP618010HU CSB-EP618010HU-B |
Recombinant Human Transcriptional enhancer factor TEF-3 (TEAD4), partial |
Yeast Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP618010HU | Recombinant Human Transcriptional enhancer factor TEF-3 (TEAD4),Partial |
E.coli |
CSB-EP618010HUa2 | Recombinant Human Transcriptional enhancer factor TEF-3 (TEAD4), partial |
E.coli |
CSB-EP618010HUe0 | Recombinant Human Transcriptional enhancer factor TEF-3 (TEAD4), partial |
E.coli |
CSB-BP618010HU | Recombinant Human Transcriptional enhancer factor TEF-3 (TEAD4), partial |
Baculovirus |
TEAD4 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP737076MO CSB-EP737076MO CSB-BP737076MO CSB-MP737076MO CSB-EP737076MO-B |
Recombinant Mouse Transcriptional enhancer factor TEF-3 (Tead4) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP737076MO2b1 | Recombinant Mouse Transcriptional enhancer factor TEF-3 (Tead4), partial |
E.coli |
CSB-EP737076MO2 | Recombinant Mouse Transcriptional enhancer factor TEF-3 (Tead4), partial |
E.coli |