TEAD4 Research Reagents

Transcriptional enhancer factor TEF-3 is a protein in humans that is encoded by TEAD4 gene. Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.

The following TEAD4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TEAD4 Antibodies

TEAD4 Antibodies for Homo sapiens (Human)

TEAD4 Antibodies for Mus musculus (Mouse)

TEAD4 Proteins

TEAD4 Proteins for Gallus gallus (Chicken)

TEAD4 Proteins for Homo sapiens (Human)

TEAD4 Proteins for Mus musculus (Mouse)

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