Recombinant Mouse Alpha-catulin (Ctnnal1)

Code CSB-YP006167MO
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP006167MO
MSDS
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Source E.coli
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Code CSB-EP006167MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP006167MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP006167MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Ctnnal1
Uniprot No.
Alternative Names
Ctnnal1; Catnal1Alpha-catulin; Alpha-catenin-related protein; ACRP; Catenin alpha-like protein 1
Species
Mus musculus (Mouse)
Expression Region
1-731
Target Protein Sequence
MAASPVPGGG GAGAVHSSNA AGFTFDSGLE IRTRSVEQTL LPLVSQITTL INHKDNTKKS DKTLQAIQRV GQAVNLAVGR FVKVGEAIAN ENWDLKEEIN IACIEAKQAG ETIASLTDVT KRSHLESDGQ VTILTDKTGV VQAARLLLSS VTKVLLLADR VVIKQIVTSR NKILATMERL EKVNSFQEFV QIFSQFGNEM VEFAHLTGDR QNDLKDEKKK ARMAVARAVL EKGTMMLLTA SKTCLRHPSC ESAHTNKEGV FDRMRVALEK VTEIVTDCRL SGETDSSSVS IFTGIKELKV NIEALRENVC FESKENLSAA LEAVLEHVED FTDSAYTSHE HRERILELSS QARTELQQLL SVWMQTQSRK TKSAAEELEL TVLKISHSLD ELRRELHCTA MQLAADLLKF HADHVVLKAL KVTGVEGNLE ALAEYACKLS EQKEQLVETC RLLRHISGTE PLEITCIHAE ETFQVTGQQI ISAAETLTLH PSSKIAKENL DVFCEAWESQ MSDMATLLRE ISDVFEGRRG ERCDHLSLPK PTKNSANLKS LKPDKPDSEE QAKIAKLGLK LGLLSSDADC EIEKWEDEEN EIVRHGRNMS RMAYSLYLFT RGEGPLKTSQ DLIHFLEVFA AEGLKLTSSV QSFSKQLKDD DKLMLLLEIN KLIPLCHQLQ TITKTSLQSK VFLKVDKCIT KIRSMMTLVV QLLSLCYKLL KKMENNRWGS ATNKDTMDGQ N
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).
Gene References into Functions
  1. Alpha-catenin has a novel role in fine-tuning of tissues' viscosity and surface tension through contractility. PMID: 23390488
  2. the interaction between alpha-catulin and alpha-dystrobrevin is evolutionarily conserved in C. elegans and mouse muscles and strongly suggests that this interaction contributes to the integrity of the dystrophin complex PMID: 22577143
  3. We observed the temporal and spatial distribution of CTNNAL1 expression in mouse lung tissue with the OVA-sensitized asthma model and found that the level of CTNNAL1 mRNA showed a prominent negative correlation with pulmonary resistance. PMID: 17647259
  4. This study identifies the E-cadherin/catenin complex as a discriminative, partly polyamine-regulated feature of IL-4/IL-13-exposed alternatively activated macrophages PMID: 19726720
Subcellular Location
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein.
Protein Families
Vinculin/alpha-catenin family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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