Recombinant Mouse Cytochrome P450 2E(Cyp2e1)

Code CSB-YP006425MO
Product Type Recombinant Protein
Size US$2474
Uniprot No. Q05421
Relevance Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias 4-nitrophenol 2-hydroxylase (EC:1.14.13.n7) CYPIIE1 Cytochrome P450-ALC Cytochrome P450-J
Species Mus musculus (Mouse)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence AVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKLAKRFGPVFTLHLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGPTWKDVRRFSLSILRDWGMGKQGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVIADILFNKRFDYDDKKCLELMSLFNENFYLLSTPWIQAYNYFSDYLQYLPGSHRKVMKNVSEIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQEPMYTMENISVTLADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYMDAVVHEIQRFINLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGKFKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTIGFGSIPREFKLCVIPRS
Research Area Others
Source Yeast
Gene Names Cyp2e1
Protein Names Recommended name: Cytochrome P450 2E1 EC= 1.14.13.- Alternative name(s): 4-nitrophenol 2-hydroxylase EC= 1.14.13.n7 CYPIIE1 Cytochrome P450-ALC Cytochrome P450-J
Expression Region 2-493aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 58.7kDa
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites.
Subcellular Location Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane, Peripheral membrane protein
Protein Families Cytochrome P450 family
Tissue Specificity Highest level in the liver and to a lesser extent in the kidney, with a higher level in the male kidney than in the female.
Database Links

KEGG: mmu:13106

STRING: 10090.ENSMUSP00000026552

UniGene: Mm.21758

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