Recombinant Mouse Growth arrest-specific protein 2 (Gas2)

Code CSB-YP009265MO
MSDS
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Source Yeast
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Code CSB-EP009265MO
MSDS
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Source E.coli
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Code CSB-EP009265MO-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP009265MO
MSDS
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Source Baculovirus
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Code CSB-MP009265MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Gas2
Uniprot No.
Alternative Names
Gas2; Gas-2Growth arrest-specific protein 2; GAS-2
Species
Mus musculus (Mouse)
Expression Region
1-314
Target Protein Sequence
MMCTALSPKV RSGPGLSDMH QYSQWLASRH EANLLPMKED LALWLTNLLG KEITAETFME KLDNGALLCQ LAATVQEKFK ESMDANKPAK TLPLKKIPCK ASAPSGSFFA RDNTANFLSW CRDLGVDETC LFESEGLVLH KQPREVCLCL LELGRIAARY GVEPPGLIKL EKEIEQEETL SAPSPSPSPS SKSSGKKSTG NLLDDAVKRI SEDPPCKCPT KFCVERLSQG RYRVGEKILF IRMLHNKHVM VRVGGGWETF AGYLLKHDPC RMLQISRVDG KTSPVQSKSP TLKDMNPDNY LVVSATYKAK KEIK
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May play a role in chondrocyte proliferation and differentiation, and in limb myogenesis. May be involved in the regulation of the apoptosis in the interdigital tissues of the developing hindlimb. May be involved in the membrane ruffling process.
Gene References into Functions
  1. GAS2 is a critical and novel regulator of tissue remodeling in the ovary during oocyte cyst breakdown and folliculogenesis PMID: 27734842
  2. these findings suggest that downregulated miR3425p is involved in regulating cell proliferation and cell cycles in Zmpste24/ MEFs by suppressing GAS2 in vitro. PMID: 28990109
Subcellular Location
Cytoplasm, cytoskeleton, stress fiber. Membrane; Peripheral membrane protein.
Protein Families
GAS2 family
Tissue Specificity
Expressed in most tissues. Highest levels in liver, lung and kidney. In the embryo strongly expressed in regions that undergo extensive apoptosis, such as the intervertebral tissues, the cranofacial mesenchyme and the cartilage of the limbs.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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