Recombinant Mouse T-cell ecto-ADP-ribosyltransferase 2 (Art2b)

Code CSB-YP518580MO
MSDS
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Source Yeast
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Code CSB-EP518580MO
MSDS
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Source E.coli
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Code CSB-EP518580MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP518580MO
MSDS
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Source Baculovirus
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Code CSB-MP518580MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Art2b
Uniprot No.
Alternative Names
Art2b; Rt6-2; Rt6.2; T-cell ecto-ADP-ribosyltransferase 2; EC 2.4.2.31; ADP-ribosyltransferase C2 and C3 toxin-like 2; ARTC2; Mono(ADP-ribosyl)transferase 2B; NAD(+) glycohydrolase; EC 3.2.2.5; T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 2; T-cell differentiation marker Rt6 homolog 2; T-cell mono(ADP-ribosyl)transferase 2
Species
Mus musculus (Mouse)
Expression Region
21-260
Target Protein Sequence
LAVPFMLDMA PNAFDDQYES CVEDMEKKAP QLLQEDFNMN EELKLEWEKA EINWKEIKNS TSYPAGFHDF HGTALVAYTG NLAIDFNRAV RDFKKSPDNF HYKAFHYYLT RAVQLLNDQG CSLVYRGTKV MFEYTGKGSV RFGQFSSSSL TKRVALSSNF FSNHGTLFII RTCLGVNIKE FSSFPREEEV LIPGYEVYHK VTAQNDNGYN EIFLDSPERK KSNFNCFYNG SAQTVNIDFS
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Has both NAD(+) glycohydrolase and ADP-ribosyltransferase activity.
Gene References into Functions
  1. Data show that shedding of T Cell Ecto-ADP-ribosyltransferase ARTC2.2 alters its substrate profile. PMID: 26209623
  2. Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway. PMID: 20975043
  3. ART2b is required for ADP-ribosylation of cell surface proteins PMID: 12370300
  4. raft association focuses ART2.2 on specific targets that constitutively or inducibly associate with lipid rafts PMID: 15657180
  5. Extracellular nicotinamide adenine dinucleotide (NAD)/ART2-dependent modification of the P2X7R purinergic receptor potentiates the ability of adenosine triphosphate (ATP) to activate the receptor, via a left shift in the ATP dose-response relationship. PMID: 19542469

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Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Protein Families
Arg-specific ADP-ribosyltransferase family
Tissue Specificity
Expressed in spleen, intestine and thymus.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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