Recombinant Rat Leucine zipper putative tumor suppressor 2 (Lzts2)

Code CSB-YP662074RA
MSDS
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Source Yeast
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Code CSB-EP662074RA
MSDS
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Source E.coli
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Code CSB-EP662074RA-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP662074RA
MSDS
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Source Baculovirus
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Code CSB-MP662074RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Lzts2
Uniprot No.
Alternative Names
Lzts2; Lapser1Leucine zipper putative tumor suppressor 2; Protein LAPSER1
Species
Rattus norvegicus (Rat)
Expression Region
1-670
Target Protein Sequence
MAIVQTLPVP LEPARETATA PQTPAMGSVS SLISGRPCPG GPAPQRHHGV PGPTFFRQQD GLLRGGYEAQ EPLCPAVPPR KTVPGNSFTY VNEDFRTESP PSPSSDVEDP REHQAHNAHL RGPPPKLIPV SGKLEKNMEK ILIRPTAFKP VLPKPRGAPS LPGFLGPRAA GLSGSQGSLT QLFGGPASSS SSSSSSSAAD KPLALSGWAS GCPSGTLSDS GRNSLSSLPT YSTGGAEPTA NSPGGHLPSH GPGRGPLPGP ARGVPTGPSH SDSGRSSSSK STGSLGARVA GGLLGSGARA SPGSSSGGDR SPPPPPPPPP SDEALLHCVL EGKLRDREAE LQQLRDSVDE SEAAVCQAFG ARQRRWPGER EDCASHAQQA TQRVQRAQQL LQLQVFQLQQ EKRQLQDDFA QLLQEREQLE RRCATFEREQ QELGPRLEET KWEVCQKSGE ISLLKQQLKE SQAELVQKGS ELVALRVALR EARAALRVSE GHARGLQEAA RARELELEAC SQELQRYRQE AEQLREKARH LDAEAAGLRE PPVPPATTDP FLLAESDEAK VQRAAAGTGG SLRAQVERLR QELQREQRRG DEQRNSFEGE RLAWQAEKEQ VIRYQKQLQH NYVQMYRRNR QLEQELQQLS LELEARELAD LGLSEPAPCI CLEEITATEI
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
Gene References into Functions
  1. LAPSER1 localizes to the centrosomes & midbodies in mitotic cells. LAPSER1 participates in cytokinesis by interacting with p80 katanin, the disruption of which may potentially cause genetic instability and cancer. PMID: 17351128
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Preferentially localized to the mother centriole. Also localized to the midbody in cells undergoing cytokinesis. Within neurons, enriched in cell bodies and localized to branch points and the tips of axonal branches.
Protein Families
LZTS2 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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