Recombinant Rat Stathmin-3 (Stmn3)

Code CSB-YP862358RA
MSDS
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Source Yeast
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Code CSB-EP862358RA
MSDS
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Source E.coli
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Code CSB-EP862358RA-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP862358RA
MSDS
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Source Baculovirus
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Code CSB-MP862358RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Stmn3
Uniprot No.
Alternative Names
Stmn3; Sclip; Stathmin-3; SCG10-like protein
Species
Rattus norvegicus (Rat)
Expression Region
1-180
Target Protein Sequence
MASTVSAYKE KMKELSVLSL ICSCFYSQPH PNTIYQYGDM EVKQLDKRAS GQSFEVILKS PSDLSPESPV LSSPPKRKDA SLEELQKRLE AAEERRKTQE AQVLKQLAER REHEREVLHK ALEENNNFSP LAEEKLNYKM ELSKEIREAH LAALRERLRE KELHAAEVRR NKEQREEMSG
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
Gene References into Functions
  1. Specific serine-proline phosphorylation and glycogen synthase kinase 3beta-directed subcellular targeting of stathmin 3/Sclip in neurons PMID: 22577147
  2. palmitoylation of stathmins 2 and 3 likely occurs at the Golgi and is crucial for their specific subcellular localization and trafficking PMID: 21471001
  3. Clusterin interacts with SCLIP in PC12 cells and the interaction may act as an important modulator during neuronal differentiation. PMID: 16038898
  4. A novel function for SCLIP in axonal morphogenesis, our results demonstrate for the first time that stathmin family proteins fulfill different and complementary roles during neuronal differentiation. PMID: 17145186
  5. SCLIP specifically accumulates in the growing dendrites of Purkinje cells (PC)during cerebellar development and is critical for both the formation and development of PC dendritic arbors at early and late stages of postnatal dendritogenesis. PMID: 18632943

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Subcellular Location
Golgi apparatus. Cell projection, growth cone. Cell projection, axon. Cytoplasm, cytosol.
Protein Families
Stathmin family
Tissue Specificity
Neuron specific.
Database Links

KEGG: rno:29246

UniGene: Rn.14961

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