Recombinant Xenopus laevis Protein atonal homolog 7-A (atoh7-a)

Code CSB-YP517522XBE
MSDS
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Source Yeast
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Code CSB-EP517522XBE
MSDS
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Source E.coli
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Code CSB-EP517522XBE-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP517522XBE
MSDS
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Source Baculovirus
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Code CSB-MP517522XBE
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
atoh7-a
Uniprot No.
Alternative Names
atoh7-a; ath5-aProtein atonal homolog 7-A; Helix-loop-helix protein xATH-5-A; Protein atonal homolog 5-A; xAth5-A
Species
Xenopus laevis (African clawed frog)
Expression Region
1-138
Target Protein Sequence
MKSDSPVHRE SHTGCQSPCP LRCLPARLEG STKRRLAANA RERRRMQGLN TAFDSLRKVV PQWGEDKQLS KYETLQMALS YIMALSRILS EAERYSRTDP EEWTNIQYDH IEEEQCLSYM EVRCPRDCDR YLPQTFSH
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Transcription factor that positively regulates the determination of retinal ganglion cell fate and formation of the optic nerve and retino-hypothalamic tract. Required for retinal circadian rhythm photoentrainment. Regulates the differentiation of olfactory receptor neurons. During retinal neurogenesis, activates the transcription of several genes such as brn3d, coe3, cbfa2t2, glis2, elrC and xgadd45-gamma.
Gene References into Functions
  1. functional comparison of Drosophila atonal, mouse and Xenopus Ath5; findings suggest atonal family may occupy a position in a gene hierarchy where differences in gene regulation or function can be correlated with evolutionary diversity of eye development PMID: 12950631
  2. Results identify a key distal Xath5 enhancer and show that this enhancer regulates the early phase of Xath5 expression, while the proximal enhancer we previously identified acts later. PMID: 19059393
Subcellular Location
Nucleus.
Database Links

KEGG: xla:378576

UniGene: Xl.176

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