Recombinant Human Intermediate conductance calcium-activated potassium channel protein 4(KCNN4)

Code CSB-CF012086HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O15554
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Purity Greater than 85% as determined by SDS-PAGE.
Research Area Cell Biology
Source in vitro E.coli expression system
Gene Names KCNN4
Protein Names Recommended name: Intermediate conductance calcium-activated potassium channel protein 4 Short name= SK4 Short name= SKCa 4 Short name= SKCa4Alternative name(s): IKCa1 Short name= IK1 KCa3.1 KCa4 Putative G
Expression Region 1-427 aa
Tag Info N-terminal 10xHis-tagged
Mol. Weight 53.7 kDa
Protein Description Full Length
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Forms a voltage-independent potassium channel that is activated by intracellular calcium
Involvement in disease Dehydrated hereditary stomatocytosis 2 (DHS2)
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families Potassium channel KCNN family, KCa3.1/KCNN4 subfamily
Tissue Specificity Widely expressed in non-excitable tissues.
Database Links

HGNC: 6293

OMIM: 602754

KEGG: hsa:3783

STRING: 9606.ENSP00000262888

UniGene: Hs.10082

Pathway Target Therapy

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