Recombinant Mouse Polypeptide N-acetylgalactosaminyltransferase 4(Galnt4)

Code CSB-CF009211MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O08832
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Mus musculus (Mouse)
Source in vitro E.coli expression system
Gene Names Galnt4
Protein Names Recommended name: Polypeptide N-acetylgalactosaminyltransferase 4 EC= Alternative name(s): Polypeptide GalNAc transferase 4 Short name= GalNAc-T4 Short name= pp-GaNTase 4 Protein-UDP acetylgalactosaminyltransferase 4 UDP-GalNAc:p
Expression Region 1-578
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward EA2 peptide substrate and a much lower activity with EPO-T, Muc2, Muc1a, Muc1b.
Subcellular Location Golgi apparatus membrane, Single-pass type II membrane protein
Protein Families Glycosyltransferase 2 family, GalNAc-T subfamily
Tissue Specificity Highly expressed in sublingual gland, stomach, colon, small intestine and cervix. Expressed at intermediate levels in kidney, ovary, lung and uterus. Weakly expressed in spleen, liver, heart and brain. Not expressed in submandibular and parotid glands, sk
Database Links

KEGG: mmu:14426

STRING: 10090.ENSMUSP00000125315

UniGene: Mm.314

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