SPZ1 Antibody

Code CSB-PA022644GA01HU
Size 100μl
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Alternative Names
SPZ1 antibody; TSP1 antibody; Spermatogenic leucine zipper protein 1 antibody; Testis-specific protein 1 antibody; Testis-specific protein NYD-TSP1 antibody
Abbreviation
SPZ1
Uniprot No.
Species
Homo sapiens (Human)
Troubleshooting
and FAQs
Storage
Store at 2-8°C. Please refer to protocol.

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Target Background

Function
(From Uniprot)
Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.
Gene References into Functions
  1. SPZ1 promotes epithelial-mesenchymal transition (EMT) by trans-activating the gene of TWIST1. A clinical analysis showed a marker association of SPZ1 and TWIST1 with induction of tumorigenesis in HCC patients. PMID: 28368406
  2. highly expressed in adult testis; may play an important role in spermatogenesis in the humans PMID: 12778315
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.
Database Links

HGNC: 30721

KEGG: hsa:84654

STRING: 9606.ENSP00000369611

UniGene: Hs.519403

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