SPZ1 Antibody

Code CSB-PA887147LA01HU
Size US$166
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  • Western blot
    All lanes: SPZ1 antibody at 4µg/ml
    Lane 1: Mouse gonadal tissue
    Lane 2: NIH/3T3 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 50 kDa
    Observed band size: 50 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA887147LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SPZ1 Polyclonal antibody
Uniprot No.
Target Names
SPZ1
Alternative Names
SPZ1 antibody; TSP1 antibody; Spermatogenic leucine zipper protein 1 antibody; Testis-specific protein 1 antibody; Testis-specific protein NYD-TSP1 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Spermatogenic leucine zipper protein 1 protein (181-430AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SPZ1 Antibody (Product code: CSB-PA887147LA01HU) is Non-conjugated. For SPZ1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA887147LB01HU SPZ1 Antibody, HRP conjugated ELISA
FITC CSB-PA887147LC01HU SPZ1 Antibody, FITC conjugated
Biotin CSB-PA887147LD01HU SPZ1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.
Gene References into Functions
  1. SPZ1 promotes epithelial-mesenchymal transition (EMT) by trans-activating the gene of TWIST1. A clinical analysis showed a marker association of SPZ1 and TWIST1 with induction of tumorigenesis in HCC patients. PMID: 28368406
  2. highly expressed in adult testis; may play an important role in spermatogenesis in the humans PMID: 12778315
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.
Database Links

HGNC: 30721

KEGG: hsa:84654

STRING: 9606.ENSP00000369611

UniGene: Hs.519403

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