Recombinant Human Spermatogenic leucine zipper protein 1 (SPZ1)

Code CSB-YP887147HU
MSDS
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Source Yeast
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Code CSB-EP887147HU
MSDS
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Source E.coli
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Code CSB-EP887147HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP887147HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP887147HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
SPZ1
Uniprot No.
Alternative Names
SPZ1; TSP1; Spermatogenic leucine zipper protein 1; Testis-specific protein 1; Testis-specific protein NYD-TSP1
Species
Homo sapiens (Human)
Expression Region
1-430
Target Protein Sequence
MASSAKSAEM PTISKTVNPT PDPHQEYLDP RITIALFEIG SHSPSSWGSL PFLKNSSHQV TEQQTAQKFN NLLKEIKDIL KNMAGFEEKI TEAKELFEET NITEDVSAHK ENIRGLDKIN EMLSTNLPVS LAPEKEDNEK KQEMILETNI TEDVSAHKEN IRGLDKINEM LSTNLPVSLA PEKEDNEKKQ QMIMENQNSE NTAQVFARDL VNRLEEKKVL NETQQSQEKA KNRLNVQEET MKIRNNMEQL LQEAEHWSKQ HTELSKLIKS YQKSQKDISE TLGNNGVGFQ TQPNNEVSAK HELEEQVKKL SHDTYSLQLM AALLENECQI LQQRVEILKE LHHQKQGTLQ EKPIQINYKQ DKKNQKPSEA KKVEMYKQNK QAMKGTFWKK DRSCRSLDVC LNKKACNTQF NIHVARKALR GKMRSASSLR
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.
Gene References into Functions
  1. SPZ1 promotes epithelial-mesenchymal transition (EMT) by trans-activating the gene of TWIST1. A clinical analysis showed a marker association of SPZ1 and TWIST1 with induction of tumorigenesis in HCC patients. PMID: 28368406
  2. highly expressed in adult testis; may play an important role in spermatogenesis in the humans PMID: 12778315
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.
Database Links

HGNC: 30721

KEGG: hsa:84654

STRING: 9606.ENSP00000369611

UniGene: Hs.519403

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