ENPP6 Antibody

Code CSB-PA064902
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA064902(ENPP6 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
ENPP6
Alternative Names
ENPP6 antibody; UNQ1889/PRO4334Glycerophosphocholine cholinephosphodiesterase ENPP6 antibody; GPC-Cpde antibody; EC 3.1.4.- antibody; EC 3.1.4.38 antibody; Choline-specific glycerophosphodiester phosphodiesterase antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 antibody; E-NPP 6 antibody; NPP-6 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human ENPP6
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:10-1:50
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids.
Gene References into Functions
  1. NPP6 has a specific role through the hydrolysis of polyunsaturated LPC, glycerophosphorylcholine, or sphingosylphosphorylcholine in kidney and brain PMID: 15788404
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor. Note=A small amount of the protein may be found in the extracellular milieu.
Protein Families
Nucleotide pyrophosphatase/phosphodiesterase family
Tissue Specificity
Predominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level).
Database Links

HGNC: 23409

OMIM: 616983

KEGG: hsa:133121

STRING: 9606.ENSP00000296741

UniGene: Hs.297814

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