KLF7 Antibody

Code CSB-PA012397LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse kidney tissue
    All lanes: KLF7 antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 34, 30, 25, 31, 14, 10 kDa
    Observed band size: 34 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) KLF7 Polyclonal antibody
Uniprot No.
Target Names
KLF7
Alternative Names
KLF7 antibody; KLF7_HUMAN antibody; Krueppel like factor 7 antibody; Krueppel-like factor 7 antibody; Kruppel like factor 7 antibody; Ubiquitous krueppel like factor antibody; Ubiquitous krueppel-like factor antibody; UKLF antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Krueppel-like factor 7 protein (114-220AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The KLF7 Antibody (Product code: CSB-PA012397LA01HU) is Non-conjugated. For KLF7 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA012397LB01HU KLF7 Antibody, HRP conjugated ELISA
FITC CSB-PA012397LC01HU KLF7 Antibody, FITC conjugated
Biotin CSB-PA012397LD01HU KLF7 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcriptional factor. Plays a critical role in neuronal morphogenesis and survival of sensory neurons. Represses the corneal epithelium differentiation. Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells. Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin.
Gene References into Functions
  1. Kruppel family member KLF7 promotes the corneal progenitor cell state; on many genes, KLF7 antagonized the corneal differentiation-promoting KLF4. PMID: 28916725
  2. KLF7 has an important role in gastric cancer (GC) progression, as it inhibits GC cell migration and may serve as a prognostic marker PMID: 28977783
  3. Higher expression of TLR4 and KLF7 may play a vital role in the process of inflammation induced by obesity in visceral adipose tissue PMID: 27714571
  4. a dominant mutation in FBXO38 causes adult-onset, progressive spinal muscular atrophy with calf predominance PMID: 24207122
  5. KLF7 was upregulated by morphine at both the transcriptional and the translational levels, promoting cell growth up to day 4 PMID: 14644156
  6. The gene encoding KLF7 is a novel candidate for conferring genetic susceptibility to type 2 diabetes. PMID: 15937668
  7. KLF7 may contribute to the pathogenesis of type 2 diabetes through an impairment of insulin biosynthesis and secretion in pancreatic beta-cells and a reduction of insulin sensitivity in peripheral tissues. PMID: 16339272
  8. We identified a novel association between the minor A-allele of KLF7 and protection against obesity in the Danish population PMID: 19147600

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Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 6350

OMIM: 604865

KEGG: hsa:8609

STRING: 9606.ENSP00000309570

UniGene: Hs.471221

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