KLF7 Antibody

Datasheet

Code	CSB-PA959499
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA959499(KLF7 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA959499(KLF7 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details
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Target Background

Product Details

Uniprot No.

O75840

Target Names

KLF7

Alternative Names

KLF7 antibody; KLF7_HUMAN antibody; Krueppel like factor 7 antibody; Krueppel-like factor 7 antibody; Kruppel like factor 7 antibody; Ubiquitous krueppel like factor antibody; Ubiquitous krueppel-like factor antibody; UKLF antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Fusion protein of Human KLF7

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:5000
IHC	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Transcriptional factor. Plays a critical role in neuronal morphogenesis and survival of sensory neurons. Represses the corneal epithelium differentiation. Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells. Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin.

Gene References into Functions

Kruppel family member KLF7 promotes the corneal progenitor cell state; on many genes, KLF7 antagonized the corneal differentiation-promoting KLF4. PMID: 28916725
KLF7 has an important role in gastric cancer (GC) progression, as it inhibits GC cell migration and may serve as a prognostic marker PMID: 28977783
Higher expression of TLR4 and KLF7 may play a vital role in the process of inflammation induced by obesity in visceral adipose tissue PMID: 27714571
a dominant mutation in FBXO38 causes adult-onset, progressive spinal muscular atrophy with calf predominance PMID: 24207122
KLF7 was upregulated by morphine at both the transcriptional and the translational levels, promoting cell growth up to day 4 PMID: 14644156
The gene encoding KLF7 is a novel candidate for conferring genetic susceptibility to type 2 diabetes. PMID: 15937668
KLF7 may contribute to the pathogenesis of type 2 diabetes through an impairment of insulin biosynthesis and secretion in pancreatic beta-cells and a reduction of insulin sensitivity in peripheral tissues. PMID: 16339272
We identified a novel association between the minor A-allele of KLF7 and protection against obesity in the Danish population PMID: 19147600

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Subcellular Location

Nucleus.

Protein Families

Krueppel C2H2-type zinc-finger protein family

Tissue Specificity

Widely expressed.

Database Links

HGNC: 6350

OMIM: 604865

KEGG: hsa:8609

STRING: 9606.ENSP00000309570

UniGene: Hs.471221

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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