Code | CSB-EL006920MO |
Size | 96T,5×96T,10×96T |
Price | Request a Quote or Start an on-line Chat |
Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now |
This mouse DKK1 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of mouse DKK1 in serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the DKK1 levels in the sample and is measured at 450 nm through a microplate reader.
DKK1 is an inhibitor of the Wnt signaling pathway. DKK1 is known for its role in head induction during development. DKK1 is essential for the formation of anterior structures and morphogenesis of the limbs in the developing embryo but is also expressed in the adult where it regulates the formation, regeneration, and repair of several tissues. DKK1 has been demonstrated to promote angiogenesis during tumorigenesis and inflammation. Deregulation of DKK1 expression is linked to metastasis of various cancers, with increased levels of DKK1 correlating with a poor prognosis in multiple myeloma, prostate cancer, and hepatocellular carcinoma.
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