Recombinant Mouse Interleukin-15 receptor subunit alpha(Il15ra),partial (Active)

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Code CSB-AP004801MO
Product Type Interleukin
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Uniprot No. Q60819
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.4
Alias Interleukin-15 receptor subunit alpha;Il15ra;sIL-15 receptor subunit alpha
Species Mus musculus (Mouse)
Biological_Activity The ED50 as determined by its ability to block human IL-15-induced proliferation of CTLL?2 mouse cytotoxic T cells is less than 10 ng/ml.
Purity Greater than 90% as determined by SDS-PAGE.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Research Area Immunology
Source Mammalian cell
Gene Names Il15ra
Expression Region 33-205aa
Tag Info C-terminal FC-tagged
Mol. Weight 45.5 kDa
Protein Description Partial
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Function High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Signal transduction involves SYK (By similarity).
Subcellular Location Membrane, Single-pass type I membrane protein, Nucleus membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Soluble interleukin-15 receptor subunit alpha: Secreted, extracellular space
Tissue Specificity Widely expressed.
Database Links

KEGG: mmu:16169

STRING: 10090.ENSMUSP00000077878

UniGene: Mm.200196

Pathway Jak-STAT signaling pathway

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