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| Code | CSB-PA861986LB01HU |
| Size | US$299 How to order? |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Homo sapiens (Human) GABARAPL1 Polyclonal antibody |
| Uniprot No. | Q9H0R8 |
| Target Names | GABARAPL1 |
| Alternative Names | APG8 like antibody; APG8L antibody; ATG8 antibody; ATG8B antibody; ATG8L antibody; Early estrogen regulated protein antibody; Early estrogen-regulated protein antibody; GABA antibody; GABA(A) receptor associated protein like 1 antibody; GABA(A) receptor-associated protein-like 1 antibody; GABARAPL1 a antibody; GABARAPL1 antibody; Gamma aminobutyric acid receptor associated protein like 1 antibody; Gamma-aminobutyric acid receptor-associated protein-like 1 antibody; GBRL1_HUMAN antibody; GEC 1 antibody; GEC-1 antibody; GEC1 antibody; Glandular epithelial cell protein 1 antibody |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Immunogen | Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 1 protein (1-117AA) |
| Immunogen Species | Homo sapiens (Human) |
| Conjugate | HRP |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | >95%, Protein G purified |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Form | Liquid |
| Tested Applications | ELISA |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.
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| Gene References into Functions |
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| Subcellular Location | Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle membrane; Lipid-anchor. Cytoplasm, cytoskeleton. Endoplasmic reticulum. Golgi apparatus. |
| Protein Families | ATG8 family |
| Tissue Specificity | Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. In the brain, expression is particularly intense in motone |
| Database Links |
HGNC: 4068 OMIM: 607420 KEGG: hsa:23710 STRING: 9606.ENSP00000266458 UniGene: Hs.524250 |
