Alternative Names
DKFZp781H1925 antibody; E2AK3_HUMAN antibody; EC 2.7.11.1 antibody; Eif2ak3 antibody; Eukaryotic translation initiation factor 2 alpha kinase 3 antibody; Eukaryotic translation initiation factor 2-alpha kinase 3 antibody; Heme regulated EIF2 alpha kinase antibody; HRI antibody; HsPEK antibody; Pancreatic eIF2 alpha kinase antibody; Pancreatic eIF2-alpha kinase antibody; PEK antibody; PRKR like endoplasmic reticulum kinase antibody; PRKR-like endoplasmic reticulum kinase antibody; WRS antibody
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from Human PERK around the phosphorylation site of T981.
Immunogen Species
Homo sapiens (Human)
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application |
Recommended Dilution |
IHC |
1:100-1:300 |
ELISA |
1:40000 |
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description
Phospho-EIF2AK3 (T981) polyclonal antibody CSB-PA000746 was produced in the rabbit immunized by using the Synthesized peptide derived from Human PERK around the phosphorylation site of T981 as the immunogen. The target protein EIF2AK3 is metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2-alpha/EIF2S1) on 'Ser-52' during the unfolded protein response (UPR) and in response to low amino acid availability. It serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1).
This Phospho-EIF2AK3 (T981) antibody was tested in the ELISA, IHC and WB. The non-conjugated IgG was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. It reacts with the Phospho-EIF2AK3 (T981) proteins of human or mouse or rat-origin and may be used to detect the endogenous levels of Phospho-EIF2AK3 (T981) protein.