Code | CSB-EP016024HU |
Abbreviation | Recombinant Human NPR2 protein, partial |
MSDS | |
Size | $224 |
Order now | |
Image |
|
Have Questions? | Leave a Message or Start an on-line Chat |
The recombinant Human NPR2 was expressed with the amino acid range of 23-458. This NPR2 protein is theoretically predicted to have a molecular weight of 64.5 kDa. The NPR2 protein was expressed in e.coli. The NPR2 coding gene included the N-terminal 6xHis-SUMO tag, which simplifies the detection and purification processes of the recombinant NPR2 protein in following stages of expression and purification.
Atrial natriuretic peptide receptor 2 (NPR2) is a membrane-bound guanylate cyclase receptor that plays a crucial role in cardiovascular regulation. Also known as natriuretic peptide receptor B (NPR-B), it primarily binds atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Upon binding, NPR2 activates the synthesis of cyclic GMP (cGMP), a second messenger that regulates various physiological processes. NPR2 is particularly important in the regulation of blood pressure, fluid homeostasis, and cardiovascular development. Mutations in the NPR2 gene are associated with certain skeletal dysplasias. Research on NPR2 extends into cardiovascular biology, endocrinology, and the development of therapeutic strategies targeting the natriuretic peptide pathway.There are currently no reviews for this product.