Recombinant Mouse Connective tissue growth factor(Ctgf),partial

In Stock
Code CSB-EP006147MOe0
Product Type Recombinant Protein
Size US$2466Purchase it in Cusabio online store
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Uniprot No. P29268
Lead Time 3-7 business days
Relevance Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes . Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells . Enhances fibroblast growth factor-induced DNA synthesis .
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias CCN family member 2Hypertrophic chondrocyte-specific protein 24Protein FISP-12
Species Mus musculus (Mouse)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence QDCSAQCQCAAEAAPHCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCVFGGSVYRSGESFQSSCKYQCTCLDGAVGCVPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDRTAVGPALAAYRLEDTFGPDPTMMRANCLVQTTEWSACSKTCGMGISTRVTNDNTFCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKIAKPVKFELSGCTSVKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEIMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMY
Research Area Cardiovascular
Source E.coli
Gene Names Ctgf
Expression Region 26-344aa
Tag Info N-terminal GST-tagged
Mol. Weight 62.0kDa
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity).
Subcellular Location Secreted, extracellular space, extracellular matrix, Secreted
Protein Families CCN family
Tissue Specificity Testis, spleen, kidney, lung, heart, and brain (lowest level in testis and highest in lung).
Database Links

KEGG: mmu:14219

STRING: 10090.ENSMUSP00000020171

UniGene: Mm.390287

Pathway Hippo signaling pathway
Apelin signaling pathway

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