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| Product Type | Recombinant Protein |
| Uniprot No. | Q60793 |
| Abbreviation | Klf4 |
| Species | Mus musculus (Mouse) |
| Gene Names | Klf4 |
| Protein Names | Recommended name: Krueppel-like factor 4 Alternative name(s): Epithelial zinc finger protein EZF Gut-enriched krueppel-like factor |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Function | Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity). |
| Subcellular Location | Nucleus |
| Protein Families | Krueppel C2H2-type zinc-finger protein family |
| Tissue Specificity | Highest expression in the colon. Lower levels in testis, lung and small intestine. |
| Database Links |
KEGG: mmu:16600 STRING: 10090.ENSMUSP00000103245 UniGene: Mm.4325 |
| Pathway | Signaling pathways regulating pluripotency of stem cells |
| Product Name | Recombinant Mouse Krueppel-like factor 4(Klf4),Yeast |
| Code | CSB-YP730657MO |
| Size | Pls inquiry other sizes |
| Source | Yeast |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | MRQPPGESDM AVSDALLPSF STFASGPAGR EKTLRPAGAP TNRWREELSH MKRLPPLPGR PYDLAATVAT DLESGGAGAA CSSNNPALLA RRETEEFNDL LDLDFILSNS LTHQESVAAT VTTSASASSS SSPASSGPAS APSTCSFSYP IRAGGDPGVA ASNTGGGLLY SRESAPPPTA PFNLADINDV SPSGGFVAEL LRPELDPVYI PPQQPQPPGG GLMGKFVLKA SLTTPGSEYS SPSVISVSKG SPDGSHPVVV APYSGGPPRM CPKIKQEAVP SCTVSRSLEA HLSAGPQLSN GHRPNTHDFP LGRQLPTRTT PTLSPEELLN SRDCHPGLPL PPGFHPHPGP NYPPFLPDQM QSQVPSLHYQ ELMPPGSCLP EEPKPKRGRR SWPRKRTATH TCDYAGCGKT YTKSSHLKAH LRTHTGEKPY HCDWDGCGWK FARSDELTRH YRKHTGHRPF QCQKCDRAFS RSDHLALHMK RHF |
| Expression Region | 1-483 |
| Protein Description | full length protein |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Mouse Krueppel-like factor 4(Klf4),E.coli |
| Code | CSB-EP730657MO |
| Size | Pls inquiry other sizes |
| Source | E.coli |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-SUMO-tagged and C-terminal Myc-tagged N-terminal His-B2M-tagged and C-terminal Myc-tagged N-terminal His-GST-tagged and C-terminal Myc-tagged N-terminal His-tagged N-terminal His-SUMO-tagged N-terminal His-B2M-tagged N-terminal His-GST-tagged N-terminal GST-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | MRQPPGESDM AVSDALLPSF STFASGPAGR EKTLRPAGAP TNRWREELSH MKRLPPLPGR PYDLAATVAT DLESGGAGAA CSSNNPALLA RRETEEFNDL LDLDFILSNS LTHQESVAAT VTTSASASSS SSPASSGPAS APSTCSFSYP IRAGGDPGVA ASNTGGGLLY SRESAPPPTA PFNLADINDV SPSGGFVAEL LRPELDPVYI PPQQPQPPGG GLMGKFVLKA SLTTPGSEYS SPSVISVSKG SPDGSHPVVV APYSGGPPRM CPKIKQEAVP SCTVSRSLEA HLSAGPQLSN GHRPNTHDFP LGRQLPTRTT PTLSPEELLN SRDCHPGLPL PPGFHPHPGP NYPPFLPDQM QSQVPSLHYQ ELMPPGSCLP EEPKPKRGRR SWPRKRTATH TCDYAGCGKT YTKSSHLKAH LRTHTGEKPY HCDWDGCGWK FARSDELTRH YRKHTGHRPF QCQKCDRAFS RSDHLALHMK RHF |
| Expression Region | 1-483 |
| Protein Description | full length protein |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Mouse Krueppel-like factor 4(Klf4),Baculovirus |
| Code | CSB-BP730657MO |
| Size | Pls inquiry other sizes |
| Source | Baculovirus |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | MRQPPGESDM AVSDALLPSF STFASGPAGR EKTLRPAGAP TNRWREELSH MKRLPPLPGR PYDLAATVAT DLESGGAGAA CSSNNPALLA RRETEEFNDL LDLDFILSNS LTHQESVAAT VTTSASASSS SSPASSGPAS APSTCSFSYP IRAGGDPGVA ASNTGGGLLY SRESAPPPTA PFNLADINDV SPSGGFVAEL LRPELDPVYI PPQQPQPPGG GLMGKFVLKA SLTTPGSEYS SPSVISVSKG SPDGSHPVVV APYSGGPPRM CPKIKQEAVP SCTVSRSLEA HLSAGPQLSN GHRPNTHDFP LGRQLPTRTT PTLSPEELLN SRDCHPGLPL PPGFHPHPGP NYPPFLPDQM QSQVPSLHYQ ELMPPGSCLP EEPKPKRGRR SWPRKRTATH TCDYAGCGKT YTKSSHLKAH LRTHTGEKPY HCDWDGCGWK FARSDELTRH YRKHTGHRPF QCQKCDRAFS RSDHLALHMK RHF |
| Expression Region | 1-483 |
| Protein Description | full length protein |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Mouse Krueppel-like factor 4(Klf4),Mammalian cell |
| Code | CSB-MP730657MO |
| Size | Pls inquiry other sizes |
| Source | Mammalian cell |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | MRQPPGESDM AVSDALLPSF STFASGPAGR EKTLRPAGAP TNRWREELSH MKRLPPLPGR PYDLAATVAT DLESGGAGAA CSSNNPALLA RRETEEFNDL LDLDFILSNS LTHQESVAAT VTTSASASSS SSPASSGPAS APSTCSFSYP IRAGGDPGVA ASNTGGGLLY SRESAPPPTA PFNLADINDV SPSGGFVAEL LRPELDPVYI PPQQPQPPGG GLMGKFVLKA SLTTPGSEYS SPSVISVSKG SPDGSHPVVV APYSGGPPRM CPKIKQEAVP SCTVSRSLEA HLSAGPQLSN GHRPNTHDFP LGRQLPTRTT PTLSPEELLN SRDCHPGLPL PPGFHPHPGP NYPPFLPDQM QSQVPSLHYQ ELMPPGSCLP EEPKPKRGRR SWPRKRTATH TCDYAGCGKT YTKSSHLKAH LRTHTGEKPY HCDWDGCGWK FARSDELTRH YRKHTGHRPF QCQKCDRAFS RSDHLALHMK RHF |
| Expression Region | 1-483 |
| Protein Description | full length protein |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
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