Recombinant Mouse Plakophilin-3 (Pkp3)

Code CSB-YP870762MO
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP870762MO
MSDS
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Source E.coli
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Code CSB-EP870762MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP870762MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP870762MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Pkp3
Uniprot No.
Alternative Names
Pkp3; Plakophilin-3
Species
Mus musculus (Mouse)
Expression Region
1-797
Target Protein Sequence
MQEGNFLLSA LQPETGVCSL ALPSDLQLDR RGAEGPEADR LRAARVQEQV RARLLQLGQQ SRHNGSAELD GSAESARGMP RGQYHTMQTG FSSRSQGMSG DKTSTFRPIA KPAYSPASWS SRSAVDLTCS RRLSSAHNGG SAFGAVGYGG TQPTPPMPTR PVSFHERGGA ASRADYDTLS LRSLRLGPGG LDDRYSVVSE QLEPAAASTY RAYAYERQAS SGSSRAGGLD WPEATEGPPS RTIRAPAMRT LQRFQSSHRS RGGTGSVSGA GLEPVARAPS VRSLSLSLAD SGHLPDVRGL DSYTGHRTLQ RLSSGFDDID LPSAVKYLMA SDPNLQVLGA AYIQHRCYSD AAAKKQARSL QAVPRLVKLF NHANQEVQRH ATGAMRNLIY DNVDNKLALV EENGIFELLR TLREQDDELR KNVTGILWNL SSSDHLKDRL ARDTLEQLTD LVLSPLSGAG GPPLIQQNAS EAEIFYNATG FLRNLSSASQ ATRQKMRECH GLVDALVTYI NHALDVGKCE DKSVENAVCV LRNLSYRLYD EMPPSALQRL EGRGRRDMAG APPGEMVGCF TPQSRRLREL PLTADALTFA EVSKDPKGLE WLWSPQIVGL YNRLLQRCEL NRHTTEAAAG ALQNITAGDR RWAGVLSRLA LEQERILNPL LDRVRTADHN QLRSLTGLIR NLSRNARNKD EMSTKVVSHL IEKLPGSVGE KCPPAEVLVN IIAVLNNLVV ASPIAARDLL YFDGLRKLVF IKKKRDSPDS EKSSRAASSL LANLWQYSKL HRDFRAKGYR KEDFLGP
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May play a role in junctional plaques.
Gene References into Functions
  1. data highlight a novel role for hematopoietic PKP3 in the regulation of both locally and systemically induced immune responses. PMID: 26173741
  2. PKP3 gene down regulation is associated with bladder cancer invasion. PMID: 22119253
  3. PKP3 plays a critical role in morphogenesis of HFs and shafts and in limiting inflammatory responses in the skin PMID: 18079750
Subcellular Location
Nucleus. Cell junction, desmosome. Note=Nuclear and associated with desmosomes.
Protein Families
Beta-catenin family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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