Code | CSB-RA200985A0HU |
Size | US$210 |
Order now | |
Image |
|
Have Questions? | Leave a Message or Start an on-line Chat |
Application | Recommended Dilution |
---|---|
IHC | 1:50-1:200 |
FC | 1:20-1:200 |
The ELANE recombinant monoclonal antibody is generated through recombinant DNA technology and can be used for the detection of human ELANE protein in ELISA, IHC, and FC assays. The gene encoding the ELANE monoclonal antibody is produced after sequencing the cDNA of the ELANE antibody-generating hybridomas, which are produced by fusing myeloma cells and B cells from an immunized animal with a synthesized peptide derived from human ELANE. The synthesized gene is then cloned into a vector and transfected into cells for cultivation. The resulting ELANE recombinant monoclonal antibody is purified through affinity chromatography from the cell culture supernatant.
The ELANE protein is a protease enzyme primarily expressed in neutrophilic granulocytes. It plays an important role in the immune system by helping to clear pathogens and damaged tissues. ELANE is also involved in the processing and activation of other immune cell-derived molecules, such as cathelicidin and defensins, which can further contribute to the clearance of pathogens and tissue damage. Excessive or uncontrolled ELANE activity can also lead to tissue damage and contribute to the development of various inflammatory and autoimmune diseases, such as acute respiratory distress syndrome (ARDS) and vasculitis.
There are currently no reviews for this product.