ELANE, also known as neutrophil elastase is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity.In human, it is encoded by the ELANE gene,which resides on chromosome 19, and it is secreted by neutrophils and macrophages during inflammation. Moreover, It also localizes to Neutrophil extracellular traps (NETs), via its high affinity for DNA, an unusual property for serine proteases. Additionally, it can modify the functions of natural killer cells, monocytes and granulocytes, and inhibits C5a-dependent neutrophil enzyme release and chemotaxis.
The following ELANE reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ELANE Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA007587LA01HU | ELANE Antibody | Human | ELISA, IHC, IF |
CSB-PA007587LB01HU | ELANE Antibody, HRP conjugated | Human | ELISA |
CSB-PA007587LC01HU | ELANE Antibody, FITC conjugated | Human | |
CSB-PA007587LD01HU | ELANE Antibody, Biotin conjugated | Human | ELISA |
CSB-RA200985A0HU | ELANE Recombinant Monoclonal Antibody | Human | ELISA, IHC, FC |
ELANE Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP007587HU | Recombinant Human Neutrophil elastase (ELANE) | E.coli |
Recombinant Human Neutrophil elastase (ELANE) | ||
CSB-YP007587HU | Recombinant Human Neutrophil elastase (ELANE) | Yeast |
CSB-EP007587HU-B | Recombinant Human Neutrophil elastase (ELANE),Biotinylated | E.coli |
ELANE Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP659740MO CSB-EP659740MO CSB-BP659740MO CSB-MP659740MO CSB-EP659740MO-B |
Recombinant Mouse Neutrophil elastase (Elane) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ELANE ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E04804m | Mouse neutrophil elastase,NE ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 0.078 ng/mL |
ELANE ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08847r | Rat neutrophil elastase,NE ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates, cell lysates | 3.12 ng/mL |
ELANE ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL007587HU | Human elastase 2, neutrophil (ELA2)ELISA kit | serum, plasma, tissue homogenates | 1.56 ng/mL |