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PAK2 is the most abundant PAK in T cells, and it has been linked to T cell function. PAK2 is required for Treg stability and the prevention of Th2-like effector cell deviation. PAK2 is an effector for the Rho family GTPases Rac and Cdc42 that regulate actin cytoskeletal remodeling. PAK2 is necessary for the formation, maturation, and timely egress of thymocytes, according to research. Apoptosis, endothelial lumen creation, viral pathogenesis, and cancer, particularly breast, hepatocarcinoma, and gastric cancer, are all influenced by PAK2 signaling.AThe production of the recombinant PAK2 antibody includes extracting RNA from spleen cells that are derived from immunized animals, reversely transcribing the RNA into DNA, sequencing and screening antibody genes, amplifying the heavy chain and light chain genes of the antibody using PCR technology, linking and cloning the genes into a plasma vector, and introducing the vector clone into a mammalian cell for functional antibody expression. The recombinant PAK2 antibody was purified using Affinity-chromatography. It can be used to detect the PAK2 antibody from Human, Mouse, Rat in the ELISA, WB, FC, IP.
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