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| Code | CSB-CF011661MO |
| Product Type | Transmembrane Protein |
| Size | Pls inquiry other sizes |
| Uniprot No. | P16382 |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Species | Mus musculus (Mouse) |
| Sequence | IKVLGEPTCFSDYIRTSTCEWFLDSAVDCSSQLCLHYRLMFFEFSENLTCIPRNSASTVCVCHMEMNRPVQSDRYQMELWAEHRQLWQGSFSPSGNVKPLAPDNLTLHTNVSDEWLLTWNNLYPSNNLLYKDLISMVNISREDNPAEFIVYNVTYKEPRLSFPINILMSGVYYTARVRVRSQILTGTWSEWSPSITWYNHFQLPLIQRLPLGVTISCLCIPLFCLFCYFSITKIKKIWWDQIPTPARSPLVAIIIQDAQVPLWDKQTRSQESTKYPHWKTCLDKLLPCLLKHRVKKKTDFPKAAPTKSLQSPGKAGWCPMEVSRTVLWPENVSVSVVRCMELFEAPVQNVEEEEDEIVKEDLSMSPENSGGCGFQESQADIMARLTENLFSDLLEAENGGLGQSALAESCSPLPSGSGQASVSWACLPMGPSEEATCQVTEQPSHPGPLSGSPAQSAPTLACTQVPLVLADNPAYRSFSDCCSPAPNPGELAPEQQQADHLEEEEPPSPADPHSSGPPMQPVESWEQILHMSVLQHGAAAGSTPAPAGGYQEFVQAVKQGAAQDPGVPGVRPSGDPGYKAFSSLLSSNGIRGDTAAAGTDDGHGGYKPFQNPVPNQSPSSVPLFTFGLDTELSPSPLNSDPPKSPPECLGLELGLKGGDWVKAPPPADQVPKPFGDDLGFGIVYSSLTCHLCGHLKQHHSQEEGGQSPIVASPGCGCCYDDRSPSLGSLSGALESCPEGIPPEANLMSAPKTPSNLSGEGKGPGHSPVPSQTTEVPVGALGIAVS |
| Source | in vitro E.coli expression system |
| Gene Names | Il4r |
| Protein Names | Recommended name: Interleukin-4 receptor subunit alpha Short name= IL-4 receptor subunit alpha Short name= IL-4R subunit alpha Short name= IL-4R-alpha Short name= IL-4RA Alternative name(s): CD_antigen= CD124 Cleaved into the following ch |
| Expression Region | 26-810 |
| Tag Info | N-terminal 10xHis-tagged |
| Protein Description | Full Length of Mature Protein |
| Storage | Store at -20°C, for extended storage, conserve at -20°C or -80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. |
| Subcellular Location | Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 2: Secreted |
| Protein Families | Type I cytokine receptor family, Type 4 subfamily |
| Tissue Specificity | Expressed in both Th1 and Th2 cells. |
| Database Links |
KEGG: mmu:16190 STRING: 10090.ENSMUSP00000033004 UniGene: Mm.233802 |
| Pathway |
Jak-STAT signaling pathway
PI3K-Akt signaling pathway Hematopoietic cell lineage Th1 and Th2 cell differentiation Th17 cell differentiation |
Il4r Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP011661MO1 CSB-EP011661MO1 CSB-BP011661MO1 CSB-MP011661MO1 |
Recombinant Mouse Interleukin-4 receptor subunit alpha(Il4r),partial | Yeast E.coli Baculovirus Mammalian cell |
Il4r ELISA Kit for Mus musculus (Mouse)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL011661MO | Mouse Interleukin-4 receptor subunit alpha(IL4R) ELISA kit | Request Information |
Recombinant Human Vascular cell adhesion protein 1(VCAM1),partial
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Human T-cell surface glycoprotein CD1c(CD1C),partial
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Human ATP synthase subunit alpha, mitochondrial(ATP5F1A)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse Peroxisome proliferator-activated receptor gamma(Pparg)
Express system: E.coli
Species: Mus musculus (Mouse)
Recombinant Human GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1(ART1)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse Sulfotransferase 1A1(Sult1a1)
Express system: E.coli
Species: Mus musculus (Mouse)
Recombinant Mouse Ras-related protein Rab-10(Rab10)
Express system: E.coli
Species: Mus musculus (Mouse)
Recombinant Human Butyrophilin subfamily 3 member A3(BTN3A3),partial
Express system: Yeast
Species: Homo sapiens (Human)
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