Recombinant Mouse P-selectin(Selp)

Code CSB-CF020978MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. Q01102
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Mus musculus (Mouse)
Source in vitro E.coli expression system
Gene Names Selp
Protein Names Recommended name: P-selectin Alternative name(s): CD62 antigen-like family member P Granule membrane protein 140 Short name= GMP-140 Leukocyte-endothelial cell adhesion molecule 3 Short name= LECAM3 Platelet activation dependent granule-ex
Expression Region 42-768
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
Subcellular Location Cell membrane, Single-pass type I membrane protein
Protein Families Selectin/LECAM family
Tissue Specificity Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Database Links

KEGG: mmu:20344

STRING: 10090.ENSMUSP00000123924

UniGene: Mm.3337

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