Recombinant Mouse Eotaxin protein(Ccl11) (Active)

In Stock
Code CSB-AP001291MO
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P48298
Lead Time 5-10 business days
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias C-C motif chemokine 11, Small-inducible cytokine A11
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 100-1000 ng/ml.
Purity >96% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Research Area Immunology
Source E.coli
Gene Names Ccl11
Expression Region 24-97aa
Tag Info Tag-Free
Mol. Weight 8.4 kDa
Protein Description Full Length of Mature Protein
PubMed ID 7568052; 8574847; 10438970; 16141072; 15489334; 9169149
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Function In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils.
Subcellular Location Secreted
Protein Families Intercrine beta (chemokine CC) family
Tissue Specificity Expressed constitutively in the thymus. Expression inducible in the lung (type I alveolar epithelial cells), intestine, heart, spleen, kidney.
Database Links

KEGG: mmu:20292

STRING: 10090.ENSMUSP00000000342

UniGene: Mm.4686

Pathway Chemokine signaling pathway
IL-17 signaling pathway

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