Rat Platelet-Derived Growth Factor A,PDGF-A ELISA kit

1. an Ntv-a transgenic rat colony was established and used to study glial brain tumors driven by two well-characterized oncogenic gene transformations, PDGFA overexpression and p53 depletion. Combined PDGFA and p53 alterations resulted in large, heterogeneous tumors in all affected animals PMID: 28358926
2. Combined inhibition of PGDF and VEGF with sunitinib prevents chronic rejection changes in experimental kidney transplantation. PMID: 26262503
3. expression altered in experimental Necrotizing enterocolitis PMID: 25899145
4. PDGF regulates vascular smooth muscle phenotype via mammalian target of rapamycin complex 1. PMID: 26032503
5. Replacing heregulin, PDGF-AA and bFGF with T3 for 6 days resulted in repression of O4, O1, Olig2 and PDGFR-a PMID: 25200619
6. observations indicated that PDGF can contribute to the development of cardiac interstitial fibrosis in the noninfarcted myocardium, but does not alter scar formation in the infarcted myocardium. PMID: 25148874
7. We detected the expression and levels of PDGF-AA, bFGF and IGF-1 in neuroblastoma cells and in conditioned media which stimulated proliferation of oligodendrocyte precursor cells. PMID: 22922759
8. PDGF-AA contained in B104 neuroblastoma cells is a key regulating molecule that instructs oligodendrocyte differentiation from embryonic stem cells through activation of Erk, PI3K, and p38 signal pathway in vitro. PMID: 21953009
9. Rad is regulated by PDGF through the transcriptional factor Egr-1 in RASMCs PMID: 21559360
10. Paraquat-treated rats showed enhanced gene expression of growth factors such as platelet-derived growth factor-A and insulin-like growth factor-1 at 21 days and transforming growth factor-beta 1 at 14 days. PMID: 20498031
11. The influence of physical exercise on the generation of PDGF-AA, in adipose tissue PMID: 20972576
12. NF-kappaB modulates the expression of PDGF-a and PDGF-B in rat retina induced by IL-1beta. PMID: 17442164
13. LPS exacerbates MWCNT-induced lung fibrosis by amplifying production of PDGF-AA in macrophages and epithelial cells, and by increasing PDGF-Ralpha on pulmonary fibroblasts PMID: 19738159
14. the PDGF/PDGF receptor system is expressed in pituitary folliculostellate cells and is involved in VEGF regulation. PMID: 19373754
15. platelet-derived growth factor-A and -B are stimulated by sphingosine 1-phosphate through S1P1-Gi-Ras-MAPK-dependent induction of Kruppel-like factor 5 PMID: 14711826
16. NHERF2 stimulates PDGF-induced proliferation by increasing PI-3-kinase/Akt, MEKindependent ERK, and Src family kinase-mediated signaling pathways PMID: 15115658
17. analysis of expression of PDGF-A, -B, -C and -D and the PDGF-receptors alpha and beta in activated rat hepatic stellate cells PMID: 16039137
18. the significance of the first expression of PDGF-A in the Leydig progenitor cells may be associated with inducing cell proliferation and migration of this cell away from the peritubular region during Leydig cell differentiation PMID: 16977580
19. These results suggest that the neurotrophic effect of platelet-derived growth factor is mediated in part via upregulation of the expression and release of secreted amyloid precursor protein alpha. PMID: 17632272
20. the inflammatory response associated with spinal cord injury in cutaneous wound healing resulted in no change in expression of platelet-derived growth factor-A at the wound site in injured rats compared to the control group PMID: 18428026
21. PDGF-A may act to mobilize oligodendrocyte progenitor cells that then respond to distinct directional signals to distribute appropriately within the CNS. PMID: 18512152
22. PTH-induced bone marrow fibrosis is mediated by PDGF-A via a phosphoinositide 3-kinase-dependent signaling pathway. PMID: 18635661
23. PDGFR (platelet derived growth factor receptor)-alpha mRNA Is Upregulated in Acutely-Rejecting, and PDGF-A and PDGF-C mRNAis upregulated in Chronically-Rejecting Cardiac Allografts PMID: 19213942
24. Report effects of lipopolysaccharide on platelet-derived growth factor isoform and receptor expression in cultured rat common bile duct fibroblasts and cholangiocytes. PMID: 19691150

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KEGG: rno:25266

STRING: 10116.ENSRNOP00000001775

UniGene: Rn.10999