ACOX1 Antibody

Code CSB-PA110823
Size US$166
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  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA110823(ACOX1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA110823(ACOX1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse stomach tissue, Mouse liver tissue, Mouse kidney tissue, Primary antibody: CSB-PA110823(ACOX1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details

Uniprot No.
Target Names
Alternative Names
ACOX antibody; ACOX1 antibody; ACOX1_HUMAN antibody; Acyl CoA oxidase 1 palmitoyl antibody; Acyl CoA oxidase straight chain antibody; AOX antibody; EC antibody; PALMCOX antibody; Palmitoyl CoA oxidase antibody; Palmitoyl-CoA oxidase antibody; Peroxisomal acyl coenzyme A oxidase 1 antibody; Peroxisomal acyl-coenzyme A oxidase 1 antibody; Peroxisomal fatty acyl CoA oxidase antibody; SCOX antibody; Straight chain acyl CoA oxidase antibody; Straight-chain acyl-CoA oxidase antibody
Raised in
Species Reactivity
Fusion protein of Human ACOX1
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen affinity purification
It differs from different batches. Please contact us to confirm it.
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Tested Applications
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
IHC 1:15-1:50
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Applications : WB

Sample type: Mice Cell

Review: Western blot aanlyses in TGF-β1-treated HK-2 cells, the protein levels of CPT1A and ACOX1 was determined, separately. Above: representative bolts; below: quantification of band intensities (mean ± S.E.M; n=3)

By Anonymous

Target Background

Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway.; Shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length.; Is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
Gene References into Functions
  1. Because patients with AOx deficiency suffer from more severe symptoms than those with X-ALD, accumulation of VLC-PUFA and/or reduction of DHA may be associated with the severity of peroxisomal diseases. PMID: 24418004
  2. ACOX1 and GNPAT silencing up-regulated ceramide galactosyltransferase (UGT8) mRNA expression, and down-regulated UDP-glucoseceramide glucosyltransferase (UGCG). PMID: 23933200
  3. Data show that human ACOX1b isoform is more effective than the ACOX1a isoform in reversing the Acox1 null phenotype in the mouse. PMID: 20195242
  4. Mutational spectrum of peroxisomal acyl-coenzyme A oxidase deficiency. PMID: 17458872
  5. report on two new patients with ACOX1 deficiency and mutational analyses PMID: 18536048

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Involvement in disease
Adrenoleukodystrophy, pseudoneonatal (Pseudo-NALD)
Subcellular Location
Protein Families
Acyl-CoA oxidase family
Tissue Specificity
Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Level
Database Links

HGNC: 119

OMIM: 264470

KEGG: hsa:51

STRING: 9606.ENSP00000293217

UniGene: Hs.464137

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