Name: GORASP2 Antibody
Brand: CUSABIO
SKU: CSB-PA002804

Product Details

Uniprot No.

Q9H8Y8

Target Names

GORASP2

Alternative Names

AW552058 antibody; DKFZp434D156 antibody; FLJ13139 antibody; Golgi phosphoprotein 6 antibody; Golgi reassembly stacking protein 2 antibody; Golgi reassembly stacking protein 2; 55kDa antibody; Golgi reassembly stacking protein of 55 kDa antibody; Golgi reassembly-stacking protein 2 antibody; Golgi reassembly-stacking protein of 55 kDa antibody; GOLPH2 antibody; GOLPH6 antibody; GORASP2 antibody; GORS2_HUMAN antibody; GRASP55 antibody; GRS2 antibody; p59 antibody; RP23-428O15.1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the Internal region of Human GRASP55.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:40000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Data

Function	Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA.
Gene References into Functions	Results demonstrate a critical role for GRASP55 and GRASP65 in maintaining the stacked structure of the Golgi, which is required for accurate posttranslational modifications in the Golgi. Additionally, the GRASP knockout cell lines developed in this study will be useful tools for studying the role of GRASP proteins in other important cellular processes. PMID: 28814501 binding site at the cleft between the PDZ1 and PDZ2 domains of GRASP65 is dominated by hydrophobic interactions with GM130 that are not observed in the GRASP55-Golgin45 complex PMID: 28049725 GRASP55 interacts with CD83 shortly after induction of dendritic cells maturation. PMID: 25701785 Cisternal-specific functions of GRASP65 and GRASP55 in continuity, compartmentalization, and function of the Golgi ribbon. PMID: 24227884 propose that GRASP55/65 are negative regulators of exocytic transport and that this slowdown helps to ensure more complete protein glycosylation in the Golgi stack and proper sorting at the trans-Golgi network PMID: 23552074 GRASP55 may function as an adaptor protein coupling MT1-MMP with furin, thus leading to the activation of the zymogen. PMID: 20608975 These results demonstrate that GRASP55 and GRASP65 stack mammalian Golgi cisternae via a common mechanism. PMID: 20083603 Data demonstrate that both GRASP55 and 65 are needed for the efficient transport to and through the Golgi complex, thus highlighting a novel role for the GRASPs in membrane trafficking. PMID: 19840934 GRASP65 is an important structural component required for maintenance of Golgi apparatus integrity PMID: 11815631 MEK1/ERK regulation of GRASP55-mediated Golgi linking is a control point in cell cycle progression PMID: 18434598 GRASP55 forms an effector complex for the small GTPase rab2, together with a conserved coiled-coil protein golgin-45 (JEM-1). PMID: 11739401 Show More Hide All
Subcellular Location	Golgi apparatus membrane, Lipid-anchor, Membrane, Peripheral membrane protein, Membrane, Lipid-anchor
Protein Families	GORASP family
Database Links	HGNC: 17500 OMIM: 608693 KEGG: hsa:26003 STRING: 9606.ENSP00000234160 UniGene: Hs.431317

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Check Code：

Code	CSB-PA002804
Size	US$167
Image	Western Blot analysis of LOVO cells using GRASP55 Polyclonal Antibody
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GORASP2 Antibody

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Target Data

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