Recombinant Human N-myc proto-oncogene protein(MYCN)

In Stock
Code CSB-YP015278HU
Product Type Recombinant Protein
Size US$2010Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P04198
Lead Time 3-7 business days
Relevance May function as a transcription factor.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias Class E basic helix-loop-helix protein 37 ;bHLHe37
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAALGPGRAQSSELILKRCLPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC
Research Area Cancer
Source Yeast
Gene Names MYCN
Protein Names Recommended name: N-myc proto-oncogene protein Alternative name(s): Class E basic helix-loop-helix protein 37 Short name= bHLHe37
Expression Region 1-464aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 51.6kDa
Protein Description Full Length
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Positively regulates the transcription of MYCNOS in neuroblastoma cells.
Involvement in disease Feingold syndrome 1 (FGLDS1)
Subcellular Location Nucleus
Tissue Specificity Expressed in the neuronal cells of the cerebrum, neuroblastomas and thyroid tumors (at protein level).
Database Links

HGNC: 7559

OMIM: 164280

KEGG: hsa:4613

STRING: 9606.ENSP00000281043

UniGene: Hs.25960

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