Recombinant Human Transcription factor SOX-9(SOX9),Baculovirus

Code CSB-BP022437HU
Product Type Recombinant Protein
Size Pls inquiry other sizes
Uniprot No. P48436
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Storage Buffer PBS pH 7.4, 50% glycerol
Species Homo sapiens (Human)
Purity >85% (SDS-PAGE)
Sequence MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI ADTSGVPSIPQTHSPQHWEQPVYTQLTRP
Source Baculovirus
Gene Names SOX9
Protein Names Recommended name: Transcription factor SOX-9
Expression Region 1-509
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Product Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Protein Description Full length protein
Target Details This protein recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
HGNC 11204
MGI 98371
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Function Transcriptional regulator
Involvement in disease Campomelic dysplasia (CMD1); 46,XX sex reversal 2 (SRXX2); 46,XY sex reversal 10 (SRXY10)
Subcellular Location Nucleus
Database Links

HGNC: 11204

OMIM: 114290

KEGG: hsa:6662

STRING: 9606.ENSP00000245479

UniGene: Hs.647409

Pathway cAMP signaling pathway

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