SOX9

Transcription factor SOX-9is a protein in humans that is encoded by SOX9 gene. SOX-9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Müllerian hormone (AMH) gene. SOX-9 also plays a pivotal role in male sexual development; by working with Sf1, SOX-9 can produce AMH in Sertoli cells to inhibit the creation of a female reproductive system. It also interacts with a few other genes to promote the development of male sexual organs. The process starts when the transcription factor Testis determining factor (encoded by the sex-determining region SRY of the Y chromosome) activates SOX-9 activity by binding to an enhancer sequence upstream of the gene. Next, Sox9 activates FGF9 and forms feedforward loops with FGF9 and PGD2.

SOX9 Antibodies

SOX9 Antibodies for Homo sapiens (Human)

SOX9 Antibodies for Human

SOX9 Proteins

SOX9 Proteins for Gallus gallus (Chicken)

SOX9 Proteins for Homo sapiens (Human)

SOX9 Proteins for Macaca mulatta (Rhesus macaque)

SOX9 Proteins for Sus scrofa (Pig)

SOX9 Proteins for Pongo pygmaeus (Bornean orangutan)

SOX9 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

SOX9 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

SOX9 Proteins for Pan troglodytes (Chimpanzee)

SOX9 Proteins for Callithrix jacchus (White-tufted-ear marmoset)

SOX9 cDNA for Canis lupus familiaris (Dog) (Canis familiaris)

Code Product Name Vector Accession NO.
CSB-CL800079DO SOX9 pUC NM_001002978.1

SOX9 cDNA for Pan troglodytes (Chimpanzee)

Code Product Name Vector Accession NO.
CSB-CL860616EQV SOX9 pUC NM_001009029.1

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