Recombinant Mouse Arginase-2, mitochondrial(Arg2)

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Code CSB-EP002006MO
Product Type Recombinant Protein
Size US$2466Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. O08691
Relevance May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP002006MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Arg2.
  • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP002006MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Arg2.
Storage Buffer Tris-based buffer,50% glycerol
Alias Kidney-type arginase;Non-hepatic arginaseType II arginase
Species Mus musculus (Mouse)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence VHSVAIVGAPFSRGQKKLGVEYGPAAIREAGLLKRLSRLGCHLKDFGDLSFTNVPQDDPYNNLVVYPRSVGLANQELAEVVSRAVSGGYSCVTMGGDHSLAIGTIIGHARHRPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIKELQDKVPQLPGFSWIKPCLSPPNIVYIGLRDVEPPEHFILKNYDIQYFSMREIDRLGIQKVMEQTFDRLIGKRQRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGVYITEEIHNTGLLSALDLVEVNPHLATSEEEAKATARLAVDVIASSFGQTREGGHIVYDHLPTPSSPHESENEECVRI
Research Area Others
Source E.coli
Gene Names Arg2
Protein Names Recommended name: Arginase-2, mitochondrial EC= 3.5.3.1 Alternative name(s): Kidney-type arginase Non-hepatic arginase Type II arginase
Expression Region 23-354aa
Tag Info N-terminal 6xHis-SUMO-tagged
Mol. Weight 52.4kDa
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells
Subcellular Location Mitochondrion
Protein Families Arginase family
Database Links

KEGG: mmu:11847

STRING: 10090.ENSMUSP00000021550

UniGene: Mm.3506

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