Recombinant Mouse Interleukin-2 receptor subunit beta(Il2rb),partial

Code CSB-EP011650MO1
Product Type Recombinant Protein
Size US$2466
Uniprot No. P16297
Relevance Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP011650MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) l2rb.
  • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP011650MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) l2rb.
Storage Buffer Tris-based buffer,50% glycerol
Alias High affinity IL-2 receptor subunit betap70-75; CD122
Species Mus musculus (Mouse)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence ASAAVKNCSHLECFYNSRANVSCMWSHEEALNVTTCHVHAKSNLRHWNKTCELTLVRQASWACNLILGSFPESQSLTSVDLLDINVVCWEEKGWRRVKTCDFHPFDNLRLVAPHSLQVLHIDTQRCNISWKVSQVSHYIEPYLEFEARRRLLGHSWEDASVLSLKQRQQWLFLEMLIPSTSYEVQVRVKAQRNNTGTWSPWSQPLTFRTRPADPMKE
Research Area Others
Source E.coli
Gene Names l2rb
Expression Region 24-240aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 29.0kDa
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Type I cytokine receptor family, Type 4 subfamily
Database Links

KEGG: mmu:16185

STRING: 10090.ENSMUSP00000086820

UniGene: Mm.35287

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation
Endocytosis

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