Recombinant Rat Fractalkine protein(Cx3cl1) (Active)

In Stock
Code CSB-AP001511RA
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. O55145
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias C-X3-C motif chemokine 1, Neurotactin, Small-inducible cytokine D1,
Species Rattus norvegicus (Rat)
Biological_Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-10 ng/ml.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG
Research Area Immunology
Source E.coli
Gene Names Cx3cl1
Expression Region 25-100aa
Tag Info Tag-Free
Mol. Weight 8.8 kDa
Protein Description Partial
PubMed ID 9724801
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Function Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV
Subcellular Location Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Processed fractalkine: Secreted
Protein Families Intercrine delta family
Tissue Specificity Highest levels in brain (neurons). Significant levels in kidney, heart, lung and adrenal gland.
Database Links

KEGG: rno:89808

STRING: 10116.ENSRNOP00000022128

UniGene: Rn.107266

Pathway Chemokine signaling pathway
TNF signaling pathway

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