Recombinant Human Carbonic anhydrase 9(CA9), partial

Code CSB-EP614990HUc0
Product Type Recombinant Protein
Size US$1726
Uniprot No. Q16790
Relevance Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP614990HUc0 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) CA9.
  • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP614990HUc0 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) CA9.
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Purity Greater than 85% as determined by SDS-PAGE.
Sequence DLPSEEDSPREEDPPGEEDLPGEEDLPGEEDLPEVKPKSEEEGSLKLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRYGGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLSDTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPR
Research Area Metabolism
Source E.coli
Gene Names CA9
Protein Names Carbonate dehydratase IXCarbonic anhydrase IX ;CA-IX ;CAIXMembrane antigen MNP54/58NRenal cell carcinoma-associated antigen G250 ;R;CC-associated antigen G250pMW1
Expression Region 64-399aa
Tag Info N-terminal 6xHis-GST-tagged
Mol. Weight 66.8 kDa
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
Subcellular Location Nucleus, Nucleus, nucleolus, Cell membrane, Single-pass type I membrane protein, Cell projection, microvillus membrane, Single-pass type I membrane protein
Protein Families Alpha-carbonic anhydrase family
Tissue Specificity Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
Database Links

HGNC: 1383

OMIM: 603179

KEGG: hsa:768

STRING: 9606.ENSP00000367608

UniGene: Hs.63287

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